FFN- Rx Fungal Free Nails Rx Now at the Advanced Foot And Ankle Center Of San Diego
Fungus Free Nails-Rx.- Fungal Free Nails, (FFN) a combination of 12 fungicidal essential oils with a patented carrier system is the only topical treatment for onychomycosis that works.
It penetrates the nail plate via the intercellular lipid layers between
the dead corneocytes and reaches the nail bed where the fungus resides.
- The initial response rate to FFN is over 90%. There are relatively few cases of resistant trichophyton, the causal organism.
- FFN needs to be applied twice daily. We tell
patients to keep the vial at their bedside and apply it upon awakening
and before going to sleep. Even though the nail may appear wet for up to
45 minutes, it has effectively penetrated in 3 minutes or less, after
which it is okay to take a bath or a shower, or put on socks.
- Reasons for initial failure include:
- Non-compliance; (50% non-compliance rate in U.S. all conditions, all meds).
- Continued microtrauma to toenails (ill-fitting shoes).
- Other than fungal etiology of pathologic nails.
- A totally dystrophic nail with involvement all of the
way back to the matrix. This nail plate is totally lifted off of the
nail bed and FFN cannot penetrate to the nail bed because of the gap.
- Initial success, witnessed by, in the first 30 days:
- Thinning of the diseased nail.
- A distinct demarcation line between normal and diseased nail.
- Dark or black spots and/or streaks in diseased nail (killed fungal elements).
- This is best documented by a digital photograph prior to onset of treatment and another one after 30 days of treatment.
- Length of treatment is dependent on the total surface area of
diseased nail and the patient’s age. The older the patient, the slower
the growth of new healthy nail. FFN does not transform diseased nail into healthy nail.
By killing the causative fungus, it hastens the crumbling of the
diseased nail over time and allows it to be replaced by new healthy nail
growth. Treatment time may vary from several months to as much as
eighteen months.
- Trichophyton, like most fungi, has a life cycle that occurs in
two stages: an active pathologic form (hyphae) and a spore form. The
hyphae produce spores which germinate over time to produce more hyphae. The spores are impervious to all medications. They exist in both the nail plate and the nail bed. Any treatment regimen has to recognize this and react accordingly. We
recommend that FFN be used twice weekly for one year after the nail
looks completely clear to kill any residual germinating spores. Our recurrence rate with full compliance is essentially zero.
- We now have available an additional formulation for onychomycosis: FFN-Rx. This formulation incorporates cyclopirox, the active element of PENLAC®, and terbenifine, the active ingredient in Lamisil®, and fluconazole, a potent killer of yeast, into FFN so these three medicinals penetrate into both the nail plate and the nail bed.
- The appropriate treatment algorithm is as follows:
- Primary failure: No sign of efficacy in first 30 days,
start FFN-Rx. In these cases the first vial will be supplied by us free
of charge (this assumes full compliance, no microtrauma to toes, etc.).
- Secondary failure: Initial success but no further
progress, i.e. probable development of resistance, patient needs FFN-Rx
available from R&S Research.
- If the nail is totally dystrophic, i.e. diseased down to the matrix, it must be continually debrided,
and FFN applied to the nail bed twice daily until the new nail grows
out completely. There is no change in treatment regimen after nail
removal. The fungus, in both active and spore form still resides in the
nail bed.
We offer an unconditional 30 day guarantee on FFN which we actually
honor for 40 days. We include the criteria for initial success on each
patient insert that accompanies each sold vial of FFN. If, for whatever
reason, you choose to honor the guarantee, we will be happy to send you
the amount of the guarantee in product at wholesale cost or twice the
equivalent thereof in product.
Q: Can I use Fungal Free Nails on my fingernails?
A: Absolutely. Fungal Free Nails is perfectly safe to be used as a
cure for fingernail fungus (also called onychomycosis). Use exactly the
same way as you would for toenails.
A: Fungal Free Nails, like all other products, has ingredients that
can and will
kill nail fungus. The problem with the other products is that they are
unable
to PENETRATE the nail in order to get to the nail bed which is where
the fungus
lives, grows and spreads. The reason the other products are
ineffective is
because they are water soluble solutions. Water cannot penetrate the
skin
(more importantly the toenail which is thick layers of skin). If water
could penetrate keratin (skin), you would blow up like a balloon
getting into a bathtub!
Fungal Free Nails can penetrate the skin because of a patent pending [see USPTO Penetrating carrier, anti-fungal composition using the same and method for treatment of dermatophytes
] carrier system that can actually go through your nail in order to
deliver the anti-fungal cure to the nail bed. Complete scientific
information about this process is available on our science page.
A: Fungal Free Nails PENETRATES the nail because it isn't a water soluble solution.
Fungal Free Nails incorporates a naturally occurring, non-toxic, lipid, non-polar,
organic solvent that carries with it the necessary lipid soluble fungicidal
essential oils to the nail bed in order to kill the fungus that is living,
growing, and spreading there.
Complete scientific information about this process is available on our science page.
For a look at the patent pending carrier system, please visit: United
States Patent and Trademark Office: Penetrating carrier, anti-fungal
composition using the same and method for treatment of dermatophytes.
A: Fungal Free Nails is All Natural, Completely Safe with No Side-Effects.
ACTIVE INGREDIENTS: Juglans regia 8x, sepia 8x, mucor
mucedo 8x, palmarosa 8x, malaleuca alternofolia, camphor, eucalyptus globulus,
anise, cinnemonum, mentha piperatum, salvia sclarae, juniper virginus, mystira
fragans, lavandula latifolia, terebinthinia oleum, vitis vinifera.
INACTIVE INGREDIENTS: Simmonsia chinensis, nujol.
All of the ingredients in Fungal Free Nails are on the FDA's Generally Regarded
as Safe (GRAS) list. Fungal Free Nails is doctor recommended, completely safe,
100% natural and non-toxic.
A: Most certainly. The unvarnished truth is that while a laser
treatment for nail fungus will temporarily improve the appearance of the
infected nail, it will almost never cure onychomycosis (nail fungus).
The laser energy necessary to kill the spores that are present under the
nail, if applied to human tissue, would cause the toe to be destroyed.
Using FFN in conjunction with laser treatment is a good idea
as FFN will continue to heal the nail after the laser treatment's
effect is over. Using FFN as directed twice daily will cure the infected
nail.
A: 30 to 35 million folks in the United States have one or more ugly discolored toenails.
A: It's not possible to guess accurately but a reasonable estimate is 2% to 18% (180 million to 1.1 billion).
A: The simple answer is that in the greatest majority of people the
condition is purely cosmetic and the major pharmaceutical companies have
historically concentrated on finding solutions to medical problems that
threaten loss of function, loss of limb, or loss of life.
A: You would think so. However, nail fungus is extremely hard to
eradicate. The most common organism that causes the condition,
Trichophyton rubrum, gets into the nail bed of the toes. Oral
prescription medications which have to be given in doses that reach a
therapeutic blood and tissue level, are expensive, have a definite side
effect profile which, although not of frequent occurrence, is
potentially dangerous, and many times either doesn't cure the problem or
if it does, the problem recurs (comes back).
A: Interestingly, the only Federal Drug Administration approved
topical medicine for the condition of nail fungus is PENLAC which,
according to its manufacturer, claims to completely cure this condition in only 5.5% of the cases in which it is used.
If you look through the package inserts or the Physicians Desk Reference
(PDR) for any other product being sold as a topical antifungal agent to
my knowledge you cannot find one that has an indication for nail
fungus.
A: The simple answer is that none of these products have satisfied
the FDA’s requirement that they prove their worth according to
established scientific criteria.
A: The reason that these antifungal products work poorly if at all is
that they are put into a water solution and applied to the nail. Since
the nail is made of keratin, which in a much less thick layer also forms
the outside layer of the skin, and keratin is not penetrable by water
the antifungal compounds don’t get to where the fungus resides, which is
the nail bed. If keratin could be penetrated by water it wouldn't be
safe for us to take bath since we would absorb water through our skin
and “blow up.” This obviously doesn't happen.
A: Keratin is does not contain living tissue cells so it can’t
actively transport any molecules. It does however have lipid or fat
channels that allow certain fat soluble molecules to pass through. These
types of fat soluble molecules exist in nature and fall into the
chemical family that includes certain organic solvents as well as
essential oils. These solvents enhance the diffusion or penetration of
the essential oils in Fungal Free Nails that have been shown to kill
nail fungus.
A: Yes! There are numerous naturally occurring plant oils that are
known to have antifungal properties and that have been shown in scientifically published studies [Journal of Photography] to kill the fungus that causes fungal nails.
A: Most definitely.
We tagged Fungal Free Nails with Turmeric, a colored food additive and
demonstrated that Fungal Free Nails penetrated the keratin of horse
hooves at ten times the rate of PENLAC. We also demonstrated almost
instantaneous complete penetration of cadaver nails in a leading
University Laboratory in California. This laboratory is the reference
laboratory (the Gold Standard) for skin and nail penetration in the
United States.
A: Unless these products contain some magical ingredient or
combination of ingredients that accelerates the growth of normal healthy
nails by a factor of five to twenty times, it is not possible. Normal
nail grows very slowly. Depending on how much of the total surface of
the nail is effected by nail fungus, the process of restoring the
appearance of the nail to its normal clear condition may take up to one
year.
A: The easiest way is to keep Fungal Free Nails at the bedside and
apply it before getting out of bed in the morning and before going to
sleep at night.
A: The fungus that causes this problem thrives under warm, moist, low
oxygen conditions. Make sure that your shoes fit properly and are well
ventilated, and that your feet and toes are dry. Shoes that are too
small will traumatize the nails and keep them from improving.
A: There are infrequent instances of extreme resistance to clearing;
these nails may take much longer to show improvement. Please let us know
if this is happening. We will advise you of what to do.
A: It took many years to figure out (1) the mechanism of nail
penetration, (2) the carrier substances that would penetrate the nail,
(3) the naturally occurring antifungal substances that would be
transported with the carrier substances to the nail bed, and (4) how to
document the results.
A: Because (a) Fungal Free Nails actually works as demonstrated in clinical
trials, and (b) it is manufactured according to the Homeopathic Pharmacopoeia
of the United States.
A: Fungal Free Nails is All Natural, Completely Safe with No Side-Effects.
ACTIVE INGREDIENTS: Juglans regia 8x, sepia 8x, mucor
mucedo 8x, palmarosa 8x, malaleuca alternofolia, camphor, eucalyptus globulus,
anise, cinnemonum, mentha piperatum, salvia sclarae, juniper virginus, mystira
fragans, lavandula latifolia, terebinthinia oleum, vitis vinifera.
INACTIVE INGREDIENTS: Simmonsia chinensis, nujol.
